| Cryopreserved arterial allografts in the treatment of major vascular infection: a comparison with conventional surgical techniques. | |
| | |
MedLine Citation:
|
PMID: 9832688 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Recent findings with cryopreserved heart valve allografts in the treatment of infectious endocarditis suggest that the use of cryopreserved arterial allografts may improve the outcome in patients with vascular infections. METHODS: Seventy-two patients with mycotic aneurysms (n = 29) or infected vascular prostheses (n = 43) of the thoracic (n = 26) or abdominal aorta (n = 46) were treated with in situ repair and extra-anatomic reconstruction using prosthetic material (n = 38) or implantation of a cryopreserved arterial allograft (n = 34). Disease-related survival and survival free of reoperation were assessed. Morbidity, cumulative lengths of intensive care, hospitalization, antibiotic treatment, and costs were calculated per year of follow-up. RESULTS: The use of cryopreserved arterial allografts was superior to conventional surgery in terms of disease-related survival (P =.008), disease-related survival free of reoperation (P =.0001), duration of intensive care per year of follow-up (median 1 vs 11 days; range 1 to 42 vs 2 to 120 days; P =.001), hospitalization (14 vs 30 days; range 7 to 150 vs 15 to 240 days; P =.002), duration of postoperative antibiotic therapy (21 vs 40 days; range 21 to 90 vs 60 to 365 days; P =.002), incidence of complications (24% vs 63%; P =.005), and elimination of infection (91% vs 53%; P =.001). In addition, costs were 40% lower in the group treated by allografts (P =.005). CONCLUSIONS: The use of cryopreserved arterial allografts is a more effective treatment for mycotic aneurysms and infected vascular prostheses than conventional surgical techniques. |
| | |
Authors:
|
P R Vogt; H P Brunner-La Rocca; T Carrel; L K von Segesser; C Ruef; J Debatin; B Seifert; W Kiowski; M I Turina |
Related Documents
:
|
10468758 - A prospective randomized study comparing absorbable and nonabsorbable staples in constr... 3387948 - Prediction of long-term complications associated with aortic valve prostheses. a 10-17 ... 20014188 - Valvular perforation in left-sided native valve infective endocarditis. 9812188 - Open-heart surgery in a growing geriatric population: patient selection and risk factor... 17870048 - Silicone intubation with or without balloon dacryocystoplasty in acquired partial nasol... 16696418 - Effectiveness of oxygenation under the drape in phacoemulsification with intraocular le... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: The Journal of thoracic and cardiovascular surgery Volume: 116 ISSN: 0022-5223 ISO Abbreviation: J. Thorac. Cardiovasc. Surg. Publication Date: 1998 Dec |
Date Detail:
|
Created Date: 1999-01-06 Completed Date: 1999-01-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0376343 Medline TA: J Thorac Cardiovasc Surg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 965-72 Citation Subset: AIM; IM |
Affiliation:
|
Clinic for Cardiovascular Surgery, the Divisions of Cardiology and Infectious Diseases, the Clinic for Radiology, and the Department of Biostatistics, ISPM, University Hospital Zurich, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Aneurysm, Infected / etiology, mortality, surgery* Aortic Aneurysm, Abdominal / etiology, surgery Aortic Aneurysm, Thoracic / etiology, surgery Arteries / cytology, transplantation* Blood Vessel Prosthesis / adverse effects* Cost-Benefit Analysis Cryopreservation* Female Follow-Up Studies Humans Male Middle Aged Prosthesis-Related Infections / etiology, mortality, surgery* Retrospective Studies Transplantation, Homologous / economics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relationship of the long thoracic nerve to the scapular tip: an aid to prevention of proximal nerve ...
Next Document: Management of vasodilatory shock after cardiac surgery: identification of predisposing factors and u...