| Cryoplasty for the prevention of arterial restenosis. | |
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MedLine Citation:
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PMID: 18535858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Restenosis after percutaneous transluminal angioplasty remains the limiting factor for the long-term benefit of endovascular therapies of peripheral arterial occlusive disease. Despite a variety of modifications and adjuncts to angioplasty such as bare metal stents, covered stents, and drug-eluting stents as well as a number of new technologies like laser angioplasty and cutting balloon angioplasty, restenosis rates have not been significantly affected and remain inferior to those for surgery for long lesions in the femoropopliteal segment. Cryoplasty, which combines balloon angioplasty with the application of cryothermal energy to the vessel wall, was suggested as a promising approach to prevent the formation of neointimal hyperplasia after angioplasty procedures. This review discusses the basic principles of cryoplasty, summarizes the current data on restenosis rates after cryoplasty treatment, and evaluates cryoplasty as a new treatment method to solve the problems associated with restenosis development. The results of the clinical studies suggest that cryoplasty is a feasible and safe technique in the treatment of femoropopliteal disease, however, they have failed to prove any superiority of cryoplasty over conventional angioplasty. |
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Authors:
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Moritz G Wildgruber; Hermann J Berger |
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Publication Detail:
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Type: Journal Article; Review Date: 2008-06-06 |
Journal Detail:
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Title: Cardiovascular and interventional radiology Volume: 31 ISSN: 1432-086X ISO Abbreviation: Cardiovasc Intervent Radiol Publication Date: 2008 Nov-Dec |
Date Detail:
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Created Date: 2008-11-07 Completed Date: 2009-03-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003538 Medline TA: Cardiovasc Intervent Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 1050-8 Citation Subset: IM |
Affiliation:
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Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Charlestown, MA 02129, USA. wildgruber.moritz@mgh.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty
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methods Animals Apoptosis Arterial Occlusive Diseases / prevention & control*, therapy Cryotherapy / methods* Graft Occlusion, Vascular / prevention & control* Humans Hyperplasia Peripheral Vascular Diseases / prevention & control*, therapy Recurrence / prevention & control Tunica Intima / pathology Vascular Patency / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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