Document Detail

Cryoirrigation in phacoemulsification facilitates a quicker cornea endothelia recovery.
MedLine Citation:
PMID:  19606169     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the recovery of cornea endothelia after phacoemulsification (phaco) with anterior chamber irrigation at different temperatures. STUDY DESIGN: A between-group design was used. PARTICIPANTS: Thirty-eight patients with cataract. METHODS: Phaco was done on 40 eyes in these patients with exactly the same procedure except for the temperature of the anterior chamber: cryoirrigation at 12 masculine C for group 1 and at room temperature (25 masculine C) for group 2, 20 eyes in each group, randomly distributed. The cornea edema, keratic precipitate (KP), and anterior chamber flare were observed with micro-slit lamp and graded on a 4-point scale at 1, 3, and 7 days after surgery and compared between groups. RESULTS: The corneas in group 1 were found to be clearer than those in group 2 at 1 and 3 days after surgery. The difference was statistically significant (p < 0.05) in favour of group 1, suggesting a lighter reaction of cornea endothelia and a quicker recovery in group 1 after the surgery with cryoirrigation. Corresponding recovery in group 2 was found to occur latterly between day 3 and day 7. However, the recovery in both groups was complete, yielding no difference between groups, at day 7 after surgery. In addition, no significant difference was found in Tyndall phenomenon and KP between groups. CONCLUSIONS: Cryoirrigation during phaco could reduce postoperative cornea edema and promote recovery. The result advocates the use of cryoirrigation in clinic.
Shu Zhang; Jian Wang; Jin Liu
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  44     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-16     Completed Date:  2009-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  446-50     Citation Subset:  IM    
Department of Ophthalmology, Second Affiliated Hospital of Nanjing Medical University, Xia Guan, Jiang Jia Yuan No. 121, Nanjing, China.
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MeSH Terms
Acetates / administration & dosage*
Aged, 80 and over
Anterior Chamber / drug effects*
Corneal Edema / prevention & control
Cryotherapy / methods*
Drug Combinations
Endothelium, Corneal / physiopathology*
Irrigation / methods
Lens Implantation, Intraocular
Middle Aged
Minerals / administration & dosage*
Postoperative Complications / prevention & control
Prospective Studies
Recovery of Function / physiology
Sodium Chloride / administration & dosage*
Visual Acuity
Reg. No./Substance:
0/Acetates; 0/BSS solution; 0/Drug Combinations; 0/Minerals; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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