Document Detail

Cryoglobulins in patients with acute hepatitis and inflammatory bowel disease.
MedLine Citation:
PMID:  7152458     Owner:  NLM     Status:  MEDLINE    
Serum cryoglobulins were detected in the majority of patients with liver disease, and in all patients with Crohn's disease and ulcerative colitis. Their incidence in acute hepatitis was similar to that in chronic active hepatitis or cirrhosis. All patients had serum cryoglobulins in the range of 5-76 micrograms/ml, except for a subgroup of patients with acute non-B hepatitis, who had much higher levels. The predominant immunoglobulin in the cryoprecipitates was IgMK. The significance of these results is discussed and possible mechanisms for the high prevalence of cryoglobulins in liver and inflammatory bowel diseases are suggested.
Y Levo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  29     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-03-17     Completed Date:  1983-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  246-8     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Colitis, Ulcerative / immunology*
Crohn Disease / immunology*
Cryoglobulins / analysis*
Hepatitis / immunology*
Hepatitis B Surface Antigens / analysis
Hepatitis, Chronic / immunology
Immunoglobulins / analysis
Liver Cirrhosis / immunology
Liver Diseases / immunology
Reg. No./Substance:
0/Cryoglobulins; 0/Hepatitis B Surface Antigens; 0/Immunoglobulins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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