Document Detail


Cryoablation vs. radiofrequency ablation for small renal masses.
MedLine Citation:
PMID:  20880723     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
RATIONALE AND OBJECTIVES: Cancer of the kidney is the third most common cancer of the urinary tract, and renal cell carcinoma is the most lethal of all genitourinary tumors. The incidental discovery of renal cell carcinoma has increased with increased use of cross-sectional imaging. Concomitantly, minimally invasive ablative technologies, including image-guided cryoablation, radiofrequency ablation, and others, have evolved as therapeutic options for small renal masses.
MATERIALS AND METHODS: Between 2006 and 2009, 111 patients (age range, 31-91 years; mean age, 70 years) underwent percutaneous computed tomography-guided thermal ablation for suspected renal cell carcinoma at two major academic centers. Outcomes data were retrospectively collected and analyzed to compare recurrence rates for patients undergoing radiofrequency ablation (n = 41) versus cryoablation (n = 70).
RESULTS: There were four cases of suspicious enhancement on follow-up computed tomography or magnetic resonance imaging in each group, with cumulative imaging recurrence rates of 11% and 7% for radiofrequency ablation and cryoablation, respectively. Log rank test analysis revealed no significant difference between rates of imaging recurrence between the two groups (P = .6044).
CONCLUSIONS: These results suggest that the use of cryoablative technology will result in similar outcomes compared with radiofrequency ablation.
Authors:
Ali Pirasteh; Laura Snyder; Nicholas Boncher; Matthew Passalacqua; David Rosenblum; J David Prologo
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Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  Academic radiology     Volume:  18     ISSN:  1878-4046     ISO Abbreviation:  Acad Radiol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440159     Medline TA:  Acad Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 AUR. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Radiology, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.
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