Document Detail

Cryoablation of atrial fibrillation.
MedLine Citation:
PMID:  21826506     Owner:  NLM     Status:  Publisher    
Atrial fibrillation (AF) is a significant burden to the public health. AF is associated with increased morbidity and mortality, including an increased risk of heart failure, stroke, cognitive impairment, and diminished quality of life. Catheter ablation is an effective therapy for recurrent, symptomatic, drug-refractory AF. To date, radiofrequency ablation has been the most common catheter-based method of pulmonary vein isolation; however, there is increasing interest in cryoablation. Emerging evidence from both observational and randomized studies suggests that cryoablation of AF is a reasonable alternative to radiofrequency ablation, with comparable safety and efficacy. The goal of this narrative review will be to trace the development of cryoablation for AF, summarize the available evidence base for both the safety and efficacy of the procedure, and finally to discuss the relative advantages and disadvantages of cryoablation versus radiofrequency ablation.
Jonathan P Piccini; James P Daubert
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-9
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  -     ISSN:  1572-8595     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Duke Center for Atrial Fibrillation/Cardiac Electrophysiology Section, Division of Cardiology, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC, USA.
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