| CryoLife-O'Brien stentless valve: 10-year results of 402 implants. | |
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MedLine Citation:
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PMID: 15734372 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: This truly stentless porcine valve is composite, without Dacron, and implanted supra-annularly. Ten-year analysis with magnetic resonance imaging is presented. METHODS: From 1992 to 2002, 402 patients (mean 73.5 years) had aortic valve replacement. Associated procedures were required in 252 patients (63%). Serial echoes provided 1340 studies. Clinical follow-up was 100%. Magnetic resonance imaging focused on aortic annulus extensibility. RESULTS: The 30-day mortality was 0.99% (4 deaths). Morbidity comprised thromboembolism (40 patients including 18 patients with permanent strokes); endocarditis (9 patients); and reoperation (9 patients [periprosthetic leak, 2; endocarditis, 5; technical needle damage, 1; and structural degeneration, 1]). Of 402 valves more than 10 years, five valves were explanted, one only for structural failure. Except for endocarditis (2 patients), no late deaths (69 patients, 1.5 months to 5.7 years) were valve related. Echocardiography demonstrated low gradients with good orifice areas, excellent ventricular regression (p = 0.0001 preoperative and postoperative comparisons) and late incompetence (mild in 45 patients and moderate in 9 patients). No living patient has severe incompetence. Magnetic resonance imaging demonstrated the annulus 'expanding and relaxing' throughout the cardiac cycle, the mean increase in cross-sectional area being 37%, resembling normal aortic root dynamics. CONCLUSIONS: Elderly patients received this hemodynamically acceptable valve with its simple, supra-annular implantation and satisfactory mid-term morbid-free lifestyle to 10 years maximum follow-up. With only one structural failure, restoration of valve annular extensibility may have a favorable influence on long-term durability. |
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Authors:
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Mark F O'Brien; Michael A H Gardner; Bruce Garlick; Homayoun Jalali; Julie A Gordon; Sarah L Whitehouse; Wendy E Strugnell; Richard Slaughter |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 79 ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-02-28 Completed Date: 2005-12-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 757-66 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiac Surgery, Brisbane, Australia. drmfobrien@bigpond.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Actuarial Analysis Aged Aged, 80 and over Aortic Valve / surgery* Bioprosthesis* Child Child, Preschool Female Follow-Up Studies Heart Valve Prosthesis* / adverse effects Humans Magnetic Resonance Imaging Male Middle Aged Postoperative Complications / epidemiology Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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