Document Detail

Cruciferous vegetable intake questionnaire improves cruciferous vegetable intake estimates.
MedLine Citation:
PMID:  17383269     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop a validated, focused Cruciferous Vegetable Food Frequency Questionnaire (FFQ) as an assessment tool for specific quantification of dietary cruciferous vegetable exposure. DESIGN/METHODS: Participants (n=107; 18 to 76 years old) completed a standard FFQ and the Cruciferous Vegetable FFQ twice over a 2-week period. Repeat dietary recalls were collected on 3 days over the same 2-week period. Urinary dithiocarbamate was determined as a biomarker of cruciferous vegetable intake. STATISTICAL ANALYSES: Descriptive statistics of intake; paired t tests and sign tests for comparison of intake estimates between instruments; Spearman correlations to assess reliability and associations between diet instruments and urinary dithiocarbamate. RESULTS: Cruciferous vegetable intake was significantly correlated between the two FFQs (r(s)=0.58), although the Cruciferous Vegetable FFQ estimated intake 35 g higher than the standard FFQ. The Cruciferous Vegetable FFQ was reliable, with a repeated measures correlation of 0.69 (P</=0.01). Urinary dithiocarbamate excretion correlated with cruciferous vegetable intake from the Cruciferous Vegetable FFQ (r(s)=0.26, P<0.01), and from the standard FFQ (r(s)=0.19, P=0.06). CONCLUSIONS: The Cruciferous Vegetable FFQ provided a reproducible, valid estimate of cruciferous vegetable exposure and improved the relationship between crucifer consumption and urinary dithiocarbamate, a biomarker of cruciferous vegetable exposure. The nearly twofold difference in exposure estimates between the Cruciferous Vegetable FFQ and the standard FFQ could change the statistical significance of risk estimates in the context of epidemiological research. This questionnaire is an appropriate research tool to evaluate cruciferous vegetable intake more accurately than a standard FFQ, particularly in the context of dietary intervention studies that promote increased vegetable intake to reduce the risk for chronic disease.
Cynthia A Thomson; Tara R Newton; Ellen J Graver; Kelly A Jackson; Phyllis M Reid; Vernon L Hartz; Ellen C Cussler; Iman A Hakim
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of the American Dietetic Association     Volume:  107     ISSN:  0002-8223     ISO Abbreviation:  J Am Diet Assoc     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-04-30     Revised Date:  2007-12-03    
Medline Journal Info:
Nlm Unique ID:  7503061     Medline TA:  J Am Diet Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  631-43     Citation Subset:  AIM; IM    
Department of Nutritional Sciences, The University of Arizona, Tucson 85721-0038, USA.
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MeSH Terms
Biological Markers / urine
Brassicaceae* / metabolism
Diet Surveys
Mental Recall
Middle Aged
Questionnaires / standards*
Reproducibility of Results
Self Disclosure
Sensitivity and Specificity
Statistics, Nonparametric
Thiocarbamates / urine*
United States
Grant Support
Reg. No./Substance:
0/Biological Markers; 0/Thiocarbamates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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