Document Detail


Crosstalk between the SUMO and ubiquitin pathways.
MedLine Citation:
PMID:  19202597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several ways in which the SUMO and ubiquitin pathways can intersect and communicate have recently been discovered. This review discusses the principles of crosstalk between SUMOylation and ubiquitination, focusing on the RNF4 family of RING finger E3 ubiquitin ligases, which specifically recognize SUMOylated proteins via their SUMO moiety for ubiquitination.
Authors:
T Hunter; H Sun
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Ernst Schering Foundation symposium proceedings     Volume:  -     ISSN:  -     ISO Abbreviation:  Ernst Schering Found Symp Proc     Publication Date:  2008  
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-03-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101312605     Medline TA:  Ernst Schering Found Symp Proc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1-16     Citation Subset:  IM    
Affiliation:
Molecular and Cell Biology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 920137-1099, USA. hunter@salk.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Protein Binding
RING Finger Domains
Signal Transduction*
Small Ubiquitin-Related Modifier Proteins / metabolism*
Ubiquitin / metabolism*
Ubiquitin-Protein Ligases / chemistry,  classification,  metabolism
Chemical
Reg. No./Substance:
0/Small Ubiquitin-Related Modifier Proteins; 0/Ubiquitin; EC 6.3.2.19/Ubiquitin-Protein Ligases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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