Document Detail


Cross-validation of MR elastography and ultrasound transient elastography in liver stiffness measurement: discrepancy in the results of cirrhotic liver.
MedLine Citation:
PMID:  22002910     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To evaluate individual differences in liver stiffness measurement using both MR elastography (MRE) and ultrasound transient elastography (UTE) in patients with chronic liver disease. MATERIALS AND METHODS: This study included 80 patients with chronic liver disease who underwent both UTE and MRE. MRE and UTE were performed using a pneumatic driver (60 Hz) and an ultrasound probe with a vibrator (50 Hz), respectively. Liver stiffness data measured using the two techniques (μ(UTE) and μ(MRE) ) were compared with respect to shear modulus. The patients were subdivided into four quartiles on the basis of average of the μ(UTE) and μ(MRE) values for each patient. RESULTS: The analysis of the 4 quartile groups revealed that μ(UTE) was significantly higher than μ(MRE) in the two most stiff liver groups: μ(UTE) versus μ(MRE) , 7.5 (1.2) versus 6.0 (0.72) kPa for the group with [μ(UTE) + μ(MRE) ]/2 of 5.6-8.0 kPa; 15.1(4.2) versus 6.7 (1.4) kPa for the group with >8.0 kPa. However, in the least stiff liver group (i.e., the group with [μ(UTE) + μ(MRE) ]/2 < 3.2 kPa), μ(UTE) was significantly lower than μ(MRE) . CONCLUSION: The shear modulus measured by UTE and MRE are not equivalent, especially in patients with stiff livers. J. Magn. Reson. Imaging 2011;. © 2011 Wiley Periodicals, Inc.
Authors:
Utaroh Motosugi; Tomoaki Ichikawa; Fumitake Amemiya; Hironobu Sou; Katsuhiro Sano; Ali Muhi; Nobuyuki Enomoto; Tsutomu Araki
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-14
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  -     ISSN:  1522-2586     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
Affiliation:
Department of Radiology, University of Yamanashi, Yamanashi, Japan. utaroh-motosugi@nifty.com.
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