Document Detail

Cross-talk between macro- and microcirculation.
MedLine Citation:
PMID:  20050837     Owner:  NLM     Status:  MEDLINE    
Physiologically, macro- and microcirculation differ markedly as macrocirculation deals with pulsatile pressure and flow and microcirculation with steady pressure and flow. Various such haemodynamic aspects correspond to a large heterogeneity in the structure and function of the vascular tree. In the past, diseases such as hypertension and diabetes mellitus were classified on the basis of the structure and function of small and large arteries. The purpose of this paper is to review the cross-talk between the micro- and macrocirculation. We shall discuss this cross-talk from the perspective of the development, physiology and pathology of the entire arterial tree.
M E Safar; H A Struijker-Boudier
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Publication Detail:
Type:  Journal Article     Date:  2009-12-26
Journal Detail:
Title:  Acta physiologica (Oxford, England)     Volume:  198     ISSN:  1748-1716     ISO Abbreviation:  Acta Physiol (Oxf)     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-27     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262545     Medline TA:  Acta Physiol (Oxf)     Country:  England    
Other Details:
Languages:  eng     Pagination:  417-30     Citation Subset:  IM    
Paris-Descartes University, Paris, France. <>
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MeSH Terms
Antihypertensive Agents / pharmacology
Diabetes Mellitus / drug therapy
Microcirculation / drug effects*,  physiology
Models, Biological
Regional Blood Flow
Reg. No./Substance:
0/Antihypertensive Agents

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