Document Detail


Cross-sectional study of vitamin D and calcium supplementation effects on chronic periodontitis.
MedLine Citation:
PMID:  19722793     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A low dietary intake of vitamin D and calcium hastens bone loss and osteoporosis. Because vitamin D metabolites may also alter the inflammatory response and have antimicrobial effects, we studied whether the use of vitamin D and calcium supplements affects periodontal disease status.
METHODS: A cohort of 51 subjects receiving periodontal maintenance therapy was recruited from two dental clinics; 23 were taking vitamin D (>or=400 IU/day) and calcium (>or=1,000 mg/day) supplementation, and 28 were not taking such supplementation. All subjects had at least two interproximal sites with >or=3 mm clinical attachment loss. Daily calcium and vitamin D intake (from food and supplements) were estimated by nutritional analysis. The following clinical parameters of periodontal disease were recorded for the mandibular posterior teeth: gingival index, probing depth, cemento-enamel junction-gingival margin distance (attachment loss), bleeding on probing, and furcation involvement. Posterior photostimulable-phosphor bitewing radiographs were taken to determine cemento-enamel junction-alveolar crest distances (alveolar crest height loss). Data were analyzed with a repeated-measures multivariate analysis of variance.
RESULTS: Compared to subjects who did not take vitamin D and calcium supplementation, supplement takers had shallower probing depths, fewer bleeding sites, lower gingival index values, fewer furcation involvements, less attachment loss, and less alveolar crest height loss. The repeated-measures analysis indicated that collectively these differences were borderline significant (P = 0.08).
CONCLUSIONS: In these subjects receiving periodontal maintenance therapy, there was a trend for better periodontal health with vitamin D and calcium supplementation. More expanded longitudinal studies are required to determine the potential of this relationship.
Authors:
D Douglas Miley; M Nathalia Garcia; Charles F Hildebolt; William D Shannon; Rex A Couture; Catherine L Anderson Spearie; Debra A Dixon; Eric M Langenwalter; Cheryl Mueller; Roberto Civitelli
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of periodontology     Volume:  80     ISSN:  0022-3492     ISO Abbreviation:  J. Periodontol.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-02     Completed Date:  2009-12-23     Revised Date:  2013-07-26    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1433-9     Citation Subset:  D; IM    
Affiliation:
Graduate Periodontics, Saint Louis University Center for Advanced Dental Education, St. Louis, MO 63104, USA. mileydd@slu.edu
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Alveolar Bone Loss / classification,  prevention & control
Alveolar Process / pathology
Calcium, Dietary / therapeutic use*
Chronic Periodontitis / classification,  prevention & control*
Cohort Studies
Cross-Sectional Studies
Dietary Supplements*
Female
Furcation Defects / classification,  prevention & control
Gingiva / pathology
Gingival Hemorrhage / classification,  prevention & control
Humans
Male
Middle Aged
Periodontal Attachment Loss / classification,  prevention & control
Periodontal Index
Periodontal Pocket / classification,  prevention & control
Radiography, Bitewing
Tooth Cervix / pathology
Vitamin D / therapeutic use*
Vitamins / therapeutic use*
Grant Support
ID/Acronym/Agency:
R21 DE016918/DE/NIDCR NIH HHS; R21 DE016918-01A2/DE/NIDCR NIH HHS; UL1 RR024992/RR/NCRR NIH HHS; UL1 RR024992/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Calcium, Dietary; 0/Vitamins; 1406-16-2/Vitamin D
Comments/Corrections
Comment In:
J Periodontol. 2011 Jun;82(6):806; author reply 806-8   [PMID:  21635160 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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