Document Detail

Cross-sectional relation of ethnicity to ventilatory function in a West London population.
MedLine Citation:
PMID:  23407230     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Urban populations worldwide are of increasingly diverse ethnicity. International recommendations suggest that ethnically specific norms should be applied when assessing spirometry, although the lower forced vital capacity (FVC) in African Americans is associated with lower survival.
OBJECTIVE: To assess differences in ventilatory function in a current, ethnically diverse British population.
METHODS: In a cross-sectional survey of three primary care practices in West London, 677 participants aged ≥40 years provided acceptable post-bronchodilator spirometric data. Ethnicity was self-defined using the British Census questions and grouped as 'White', 'African-Caribbean' and 'Other'.
RESULTS: After adjustment, the ratio of 1-second forced expiratory volume (FEV(1)) to FVC was 1.0% (95%CI -2.5 to 4.5) higher in Black men and 1.8% (-0.8 to 4.4) higher in Black women compared with the White population. In contrast, FVC was 870 ml (-1140 to -600) lower in Black men and 590 ml (-760 to -420) lower in Black women. Participants from 'Other' ethnic groups had results similar to those of Black participants.
CONCLUSIONS: The FEV(1)/FVC ratio can be used without regard to ethnic background to assess obstruction. However, FVC is systematically lower in all minority ethnic groups.
R Hooper; P Burney
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease     Volume:  17     ISSN:  1815-7920     ISO Abbreviation:  Int. J. Tuberc. Lung Dis.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706389     Medline TA:  Int J Tuberc Lung Dis     Country:  France    
Other Details:
Languages:  eng     Pagination:  400-5     Citation Subset:  IM    
Centre for Primary Care & Public Health, Queen Mary University of London, London, UK.
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