Document Detail

Cross-sectional echocardiographic left ventricular geometry in rheumatic mitral stenosis.
MedLine Citation:
PMID:  8444506     Owner:  NLM     Status:  MEDLINE    
The ultrastructural myopathic changes and deranged left ventricular contractile function have been reported in patients with rheumatic mitral stenosis. It is not clear if as a result of these myopathic changes, global left ventricular myocardial remodelling occurs to alter its normal elliptical shape in the absence of qualitative segmental asynchrony. To study the left ventricular cavity shape independent of chamber size, cross-sectional echocardiographically measured longest long axis (L) of the left ventricular cavity in the apical four-chamber view and short axis diameters at the level of tips of the mitral leaflets in the parasternal long axis view (D-1), of the basal cavity (D-2) and the apical segment (D-3) in the apical four-chamber view at end-diastole and their ratio, were studied in 20 patients with isolated rheumatic mitral stenosis. Twenty healthy volunteers matched for age, sex, heart rate, height and body surface area provided the normal control data. The patients with mitral stenosis had shorter long axis diameter (7.2 +/- 0.7 vs 7.9 +/- 0.5 cm, p < 0.001) and greater short axis/long axis diameter ratios at every level with the most pronounced change in the apical segment of the cavity (D-3/L 0.49 +/- 0.09 vs 0.40 +/- 0.05, p < 0.001). Left ventricular end-diastolic sphericity index was also markedly increased in the patients with mitral stenosis (0.57 +/- 0.09 vs 0.40 +/- 0.05, p < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
J C Mohan; R Agrawala; R Calton; R Arora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  38     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-04-07     Completed Date:  1993-04-07     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  81-7     Citation Subset:  IM    
Department of Cardiology, G.B. Pant Hospital, New Delhi, India.
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MeSH Terms
Body Height
Body Surface Area
Echocardiography* / methods
Heart Rate
Middle Aged
Mitral Valve Stenosis / pathology,  physiopathology,  ultrasonography*
Observer Variation
Prospective Studies
Rheumatic Heart Disease / pathology,  physiopathology,  ultrasonography*
Sensitivity and Specificity
Severity of Illness Index
Stroke Volume
Ventricular Function, Left

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