| Cross-reactive T-cell antigens among mammalian species. | |
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MedLine Citation:
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PMID: 59778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fluoresceinated heteroantisera prepared against T cells of rats, monkeys, and humans were reacted withthymus and spleen cells from 11 selected species. These reagents recognized cross-reacting T cell antigen(s) among rodent species (mouse, rat, guinea pig, and hamster) and among primate species (monkey and humans). With one exception, the cross-reactivity was restricted to a phylogenetic order. All three antisera required relatively few absorptions to achieve T cell specificity for related species when compared to absorption requirements for the isologous species. Differentiation antigens within a phylogenetic order thus appear to be more homologous than other cell surface constituents on T cells. |
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Authors:
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C M Balch; M K Dagg; M D Cooper |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of immunology (Baltimore, Md. : 1950) Volume: 117 ISSN: 0022-1767 ISO Abbreviation: J. Immunol. Publication Date: 1976 Aug |
Date Detail:
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Created Date: 1976-10-02 Completed Date: 1976-10-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985117R Medline TA: J Immunol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 447-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorption Animals Antigens Antilymphocyte Serum Cross Reactions Epitopes* Haplorhini Humans Primates Rats Rodentia Species Specificity Spleen / cytology T-Lymphocytes / immunology* Thymus Gland / cytology |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 0/Antilymphocyte Serum; 0/Epitopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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