Document Detail


Cross-protection of infant mice against intestinal colonisation by Campylobacter jejuni: importance of heat-labile serotyping (Lior) antigens.
MedLine Citation:
PMID:  3398033     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An association of the heat-labile antigens detected by the Lior serotyping scheme with ability to protect infant mice against gastrointestinal colonisation with Campylobacter jejuni has been established. Overall, 39 (57%) of 68 infant mice challenged with a heterologous strain of the same Lior serotype as the vaccine strain were protected, compared with 40 (85%) of 47 infants protected against a homologous challenge. In contrast, none of the infant mice challenged with a strain carrying the same heat-stable antigens (i.e., of the same Penner serotype as the vaccine strain) were protected.
Authors:
A G Abimiku; J M Dolby
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical microbiology     Volume:  26     ISSN:  0022-2615     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  1988 Aug 
Date Detail:
Created Date:  1988-09-06     Completed Date:  1988-09-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  265-8     Citation Subset:  IM    
Affiliation:
Division of Communicable Diseases, MRC Clinical Research Centre, Harrow, Middlesex.
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MeSH Terms
Descriptor/Qualifier:
Agglutination Tests
Animals
Animals, Newborn / immunology
Antigens, Bacterial / immunology*
Bacterial Vaccines / immunology*
Campylobacter fetus / classification,  immunology*
Hot Temperature
Intestines / microbiology*
Mice
Serotyping
Chemical
Reg. No./Substance:
0/Antigens, Bacterial; 0/Bacterial Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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