Document Detail

Cross-over trials in Statistics in Medicine: the first '25' years.
MedLine Citation:
PMID:  16955535     Owner:  NLM     Status:  MEDLINE    
Papers on cross-over trials that have appeared in the first 25 years of Statistics in Medicine are reviewed. Papers on bioequivalence are also considered. After a brief statistical summary, individual papers are discussed under seven headings: 1. The two-stage analysis of AB/BA trials, 2. Baselines, 3. Binary and categorical data, 4. Survival data, 5. Modelling carry-over, 6. Bioequivalence and 7. Components of variation. Finally, a brief assessment of the importance in this field of Statistics in Medicine is given.
Stephen Senn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Statistics in medicine     Volume:  25     ISSN:  0277-6715     ISO Abbreviation:  Stat Med     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-27     Completed Date:  2007-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8215016     Medline TA:  Stat Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  3430-42     Citation Subset:  IM    
Department of Statistics, University of Glasgow, Glasgow G12 8QQ, UK.
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MeSH Terms
Cross-Over Studies*
Journalism, Medical*
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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