Document Detail


Cross-fostering effects on weight, exploratory activity, acoustic startle reflex and corticosterone stress response in Norway gray rats selected for elimination and for enhancement of aggressiveness towards human.
MedLine Citation:
PMID:  19096923     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two rat lines, one tame, the other aggressive, differing by many behavioral features and stress reactivity were developed by long-term selection of wild gray rats for elimination and enhancement of aggressiveness towards humans. The aim of this work was to study the role of the maternal environment in the expression of these differences between the two rat lines using the cross-fostering paradigm. Fostering of tame rats of both sexes by aggressive mothers and aggressive females by tame mothers was without effect on behavior score towards humans, but the cross-fostered aggressive males had a small, yet significant, increase in aggressiveness score. Cross-fostering revealed that exploratory behavior in the hole-board test and the acoustic startle amplitude were weakly affected by maternal interactions, although there was an effect on body weight and on the stress corticosterone response. Body weight was decreased in tame males fostered by aggressive mothers only and it was increased in cross-fostered aggressive rats of both sexes. Fostering of tame males and females by an aggressive mother enhanced almost twofold the corticosterone response immediately after stress, while fostering of aggressive ratlings of both sexes by a tame mother was without effect. The current results demonstrated that the maternal postnatal environment had no substantial effect on the behavioral responses of both tame and aggressive rats, but it possibly contributed to the development of the corticosterone response to restraint stress in the tame, and not the aggressive rats, i.e. these effects of cross-fostering were dependent on ratling genotype.
Authors:
Irina Z Plyusnina; Irina N Oskina; Marina A Tibeikina; Nina K Popova
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-12-19
Journal Detail:
Title:  Behavior genetics     Volume:  39     ISSN:  1573-3297     ISO Abbreviation:  Behav. Genet.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-02-05     Completed Date:  2009-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0251711     Medline TA:  Behav Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  202-12     Citation Subset:  IM    
Affiliation:
Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. iplysn@bionet.nsc.ru
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MeSH Terms
Descriptor/Qualifier:
Acoustics
Aggression
Animals
Behavior, Animal
Corticosterone / blood*
Female
Genotype
Humans
Male
Rats
Reflex, Acoustic
Startle Reaction
Chemical
Reg. No./Substance:
50-22-6/Corticosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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