| Cross-calibration of GE/Lunar pencil and fan-beam dual energy densitometers--bone mineral density and body composition studies. | |
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MedLine Citation:
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PMID: 12879093 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: In vitro and in vivo comparisons of bone mineral density (BMD) and body composition between GE/Lunar pencil (DPXL) and fan-beam (PRODIGY) absorptiometers. DESIGN: Comparison of BMD, bone mineral content (BMC) and area of lumbar spine (L2-L4), femoral neck and total body. Total body composition compartments tissue (TBTissue), fat (TBF), lean tissue (TBLean) and %TBF were also compared. SETTING: Centre for Bone and Body Composition Research, University of Leeds. PHANTOMS/SUBJECTS: A range of spine phantoms, a variable composition phantom (VCP) and total body phantom. A total of 72 subjects were included for the in vivo study. RESULTS: In vitro: A small significant underestimation of BMD by the Prodigy compared to the DPXL ranging from 0.7 to 2% (p<0.05-0.001) for the spine phantoms. The Prodigy underestimated the VCP %Fat. Although the Prodigy underestimated phantom TBBMD by 1.1+/-1.0%, TBBMC and area were reduced by 8.2+/-1.4 and 7.3+/-1.0%, respectively. The Prodigy overestimated TBTissue 1508 g (2.2%), TBLean 588 g (1.2%), TBF 919 g (4.8%) and %TBF (0.8%). In vivo: BMD cross-calibration was only required in the femoral neck, DPXL(BMD)=0.08+0.906*PRODIGY(BMD). The Prodigy had higher estimates for TBTissue 1360 g (2.3%), TBLean 840 g (2.0%), TBF 519 g (3.4%), TBBMC 32.8 g (1.3%) and %TBF (0.3%). Cross-calibration equations were required for TBTissue(DPXL)=-1158+0.997*TBTissue(PRODIGY) and TBBMC(DPXL)= 89.7+0.949*TBBMC(PRODIGY). CONCLUSIONS: Small differences between the two absorptiometers for both BMD and body composition can be made compatible by use of cross-calibration equations and factors. The discrepancy in body composition compartments requires further research. |
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Authors:
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B Oldroyd; A H Smith; J G Truscott |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of clinical nutrition Volume: 57 ISSN: 0954-3007 ISO Abbreviation: Eur J Clin Nutr Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-07-24 Completed Date: 2003-12-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8804070 Medline TA: Eur J Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 977-87 Citation Subset: IM |
Affiliation:
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Centre for Bone and Body Composition Research, University of Leeds, UK. bo@medphysics.leeds.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon
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instrumentation,
methods,
standards* Adolescent Adult Aged Body Composition* Bone Density* Calibration Confidence Intervals Female Femur Neck / radiography Humans Lumbar Vertebrae / radiography Male Middle Aged Phantoms, Imaging Reproducibility of Results Sensitivity and Specificity Spine / radiography |
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