Document Detail


Cross-calibration of GE/Lunar pencil and fan-beam dual energy densitometers--bone mineral density and body composition studies.
MedLine Citation:
PMID:  12879093     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In vitro and in vivo comparisons of bone mineral density (BMD) and body composition between GE/Lunar pencil (DPXL) and fan-beam (PRODIGY) absorptiometers. DESIGN: Comparison of BMD, bone mineral content (BMC) and area of lumbar spine (L2-L4), femoral neck and total body. Total body composition compartments tissue (TBTissue), fat (TBF), lean tissue (TBLean) and %TBF were also compared. SETTING: Centre for Bone and Body Composition Research, University of Leeds. PHANTOMS/SUBJECTS: A range of spine phantoms, a variable composition phantom (VCP) and total body phantom. A total of 72 subjects were included for the in vivo study. RESULTS: In vitro: A small significant underestimation of BMD by the Prodigy compared to the DPXL ranging from 0.7 to 2% (p<0.05-0.001) for the spine phantoms. The Prodigy underestimated the VCP %Fat. Although the Prodigy underestimated phantom TBBMD by 1.1+/-1.0%, TBBMC and area were reduced by 8.2+/-1.4 and 7.3+/-1.0%, respectively. The Prodigy overestimated TBTissue 1508 g (2.2%), TBLean 588 g (1.2%), TBF 919 g (4.8%) and %TBF (0.8%). In vivo: BMD cross-calibration was only required in the femoral neck, DPXL(BMD)=0.08+0.906*PRODIGY(BMD). The Prodigy had higher estimates for TBTissue 1360 g (2.3%), TBLean 840 g (2.0%), TBF 519 g (3.4%), TBBMC 32.8 g (1.3%) and %TBF (0.3%). Cross-calibration equations were required for TBTissue(DPXL)=-1158+0.997*TBTissue(PRODIGY) and TBBMC(DPXL)= 89.7+0.949*TBBMC(PRODIGY). CONCLUSIONS: Small differences between the two absorptiometers for both BMD and body composition can be made compatible by use of cross-calibration equations and factors. The discrepancy in body composition compartments requires further research.
Authors:
B Oldroyd; A H Smith; J G Truscott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  57     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-07-24     Completed Date:  2003-12-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  977-87     Citation Subset:  IM    
Affiliation:
Centre for Bone and Body Composition Research, University of Leeds, UK. bo@medphysics.leeds.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Absorptiometry, Photon / instrumentation,  methods,  standards*
Adolescent
Adult
Aged
Body Composition*
Bone Density*
Calibration
Confidence Intervals
Female
Femur Neck / radiography
Humans
Lumbar Vertebrae / radiography
Male
Middle Aged
Phantoms, Imaging
Reproducibility of Results
Sensitivity and Specificity
Spine / radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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