| Cross allergy between paranitro compounds with special reference to DNCB and chloramphenicol. | |
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MedLine Citation:
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PMID: 657786 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cross allergy between paranitro compounds including DNCB and chloramphenicol, was studied in 42 patients. A total of 27 had been primarily sensitized to DNCB, and 15 patients with eczema exhibited a delayed-type reaction to chloramphenicol, showing a positive patch test. All 15 patients with chloramphenicol allergy cross reacted with chloramphenicol succinate and chloramphenicol palmitate. Three of them cross reacted with paranitrobenzoic acid, and two of these also with paradinitrobenzene. None of the 15 patients cross reacted with DNCB in acetone or DNCB in petrolatum, and none reacted to picric acid, paranitrophenol or dinitroorthocresol. The 27 patients primarily sensitized to DNCB did not cross react with any of the paranitro compounds studied, in particular not with chloramphenicol or its salts. Thus, the study confirms the specificity of the DNCB sensitivity. |
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Authors:
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K Eriksen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Contact dermatitis Volume: 4 ISSN: 0105-1873 ISO Abbreviation: Contact Derm. Publication Date: 1978 Feb |
Date Detail:
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Created Date: 1978-08-14 Completed Date: 1978-08-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7604950 Medline TA: Contact Dermatitis Country: DENMARK |
Other Details:
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Languages: eng Pagination: 29-32 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Chloramphenicol / immunology* Cross Reactions Dinitrochlorobenzene / immunology* Drug Hypersensitivity / etiology, immunology* Eczema / immunology Female Humans Hypersensitivity, Delayed / etiology Male Middle Aged Nitro Compounds / immunology* Nitrobenzenes / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Nitro Compounds; 0/Nitrobenzenes; 56-75-7/Chloramphenicol; 97-00-7/Dinitrochlorobenzene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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