Document Detail

Cross-Sectional Survey of Workers Exposed to Aliphatic Diisocyanates Using Detailed Respiratory Medical History and Questions Regarding Accidental Skin and Respiratory Exposures.
MedLine Citation:
PMID:  24351890     Owner:  NLM     Status:  Publisher    
OBJECTIVES:: To identify possible cases of occupational asthma and assess accidental skin and inhalation exposures to aliphatic diisocyanates.
METHODS:: Seventy-three employees from two plants, manufacturing or producing aliphatic diisocyanates, were surveyed using a detailed respiratory history questionnaire with additional questions on accidental skin and inhalation exposures. Further reviews of medical records and interviews were used to determine whether any of 15 employees with questionable responses had developed occupational asthma.
RESULTS:: No cases of occupational asthma were identified. Nevertheless, many employees reported occasional accidental unprotected skin exposures and/or detecting the odor of 1,6-hexamethylene diisocyanate or isophorone diisocyanate.
CONCLUSIONS:: Consistent with a previous study, no cases of occupational asthma were identified from exposure to 1,6-hexamethylene diisocyanate, isophorone diisocyanate, methylene bis(4-cyclohexyl isocyanate), or their polyisocyanates even though many employees reported detection of odors (93%) or skin exposures (53%).
James A Hathaway; Donald M Molenaar; Laura D Cassidy; Timothy M Feeley; Barbara J Cummings
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-12-17
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  -     ISSN:  1536-5948     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2013 Dec 
Date Detail:
Created Date:  2013-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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