Document Detail

Cronkhite-Canada syndrome associated with a rectal cancer and adenomatous changes in colonic polyps.
MedLine Citation:
PMID:  3970299     Owner:  NLM     Status:  MEDLINE    
A 52-year-old man with the clinical features of Cronkhite-Canada syndrome developed rectal cancer. Radiologic and endoscopic examinations revealed gastrointestinal polyposis. Histologic examination of the biopsied polyps showed cystic dilatation of glands with an inflammatory stroma. A later biopsy from a rectal polyp proved to be an adenocarcinoma. The totally resected colon and upper rectum had an ulcerated rectal cancer and numerous polyps; most of the polyps showed histological changes typical of the syndrome. Only three polyps had adenomatous changes at their surfaces. Adenomatous and carcinomatous changes of epithelia can occur in non-neoplastic polyposis of Cronkhite-Canada syndrome from which presumably a carcinoma can develop, as in the present case.
Y Katayama; M Kimura; M Konn
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of surgical pathology     Volume:  9     ISSN:  0147-5185     ISO Abbreviation:  Am. J. Surg. Pathol.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-03-14     Completed Date:  1985-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7707904     Medline TA:  Am J Surg Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  65-71     Citation Subset:  IM    
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MeSH Terms
Adenocarcinoma / pathology*
Alopecia / complications
Colon / pathology
Colonic Polyps / complications,  pathology*
Middle Aged
Pigmentation Disorders / complications
Polyps / complications,  pathology*
Rectal Neoplasms / pathology*
Rectum / pathology
Stomach Neoplasms / complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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