Document Detail

Crohn's disease and pregnancy.
MedLine Citation:
PMID:  5069636     Owner:  NLM     Status:  MEDLINE    
This paper reports the outcome of 60 pregnancies in 40 women, all of whom had concomitant Crohn's disease. Detailed analysis of pregnancy rates in Crohn's disease supports in outline the hypothesis that some patients with bowel symptoms may be rendered temporarily subfertile by the activity of their bowel complaints. In contrast there is little or no evidence of any adverse effect during pregnancy on mother or child. Most pregnancies went normally to term and, if anything, Crohn's disease tended to improve during the period of confinement.After delivery, however, over 40% of patients suffered a relapse of Crohn's disease. Such a situation might well constitute a logical indication for the administration of corticosteroid therapy.
F T De Dombal; I L Burton; J C Goligher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  3     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1972 Sep 
Date Detail:
Created Date:  1972-11-10     Completed Date:  1972-11-10     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  550-3     Citation Subset:  AIM; IM    
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Crohn Disease* / complications,  drug therapy,  surgery
Delivery, Obstetric
Follow-Up Studies
Infertility, Female / etiology
Middle Aged
Pregnancy Complications*
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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