Document Detail

Crohn disease: early recognition and progress of aphthous lesions.
MedLine Citation:
PMID:  8284398     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To clarify the radiographic appearance of the initial change an dprogression in Crohn disease. MATERIALS AND METHODS: Between 1984 and 1992, nine patients (seven men and two women, aged 16-34 years; mean, 20 years) with Crohn disease, who had evidence of only aphthous erosions or ulcers at the initial examination, underwent repeated radiography for up to 7 years 11 months (median, 4 years). RESULTS: In all patients, the stomach, duodenum, small intestine, and colorectum were involved, and the esophagus was affected in three patients. Subsequently, four of the nine patients had lesions that progressed from aphthous lesions to overt Crohn disease, including ileitis in two patients, colitis in one, and ileocolitis in one. Time intervals between the first visit and the progression varied from 9 months to 3 years 6 months. In all eight patients who underwent nutritional treatment, regression of the lesions was recognized, but three of the lesions progressed during interruption of the nutritional diet. CONCLUSION: Crohn disease may initially appear as diffuse aphthous lesions in the gastrointestinal mucosa.
K Hizawa; M Iida; N Kohrogi; F Kuroki; T Yao; K Sakamoto; M Fujishima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  190     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-02-17     Completed Date:  1994-02-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  451-4     Citation Subset:  AIM; IM    
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Barium Sulfate / diagnostic use
Colon / pathology,  radiography
Crohn Disease / radiography*
Digestive System / pathology,  radiography
Follow-Up Studies
Ulcer / pathology,  radiography
Reg. No./Substance:
7727-43-7/Barium Sulfate

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