Document Detail


Critique: measuring hydrogen stable isotope abundance of proteins to infer origins of wildlife, food and people.
MedLine Citation:
PMID:  23534421     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Measurement of the relative abundance of (2)H (expressed in δ (2)H values) in tissues of plants, wildlife and people has evolved into a powerful forensic tool. The approach is based on the strong linkage between spatial patterns of δ (2)H values in precipitation at local and continental scales, and the tissues of plants and animals produced on these 'isoscapes'. Unfortunately, despite this exciting potential, difficulties inherent in the measurement of δ (2)H values in complex organic materials such as proteins, as well as the accuracy of such measurements, and a reluctance to adopt strict quality assurance/QC approaches to address challenges associated with these measurements, has clearly limited this potential. These challenges are entirely avoidable and techniques now exist for the routine reliable measurement of δ (2)H values in materials of forensic interest that will allow completely comparable data among laboratories.
Authors:
Wolfram Meier-Augenstein; Keith A Hobson; Leonard I Wassenaar
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bioanalysis     Volume:  5     ISSN:  1757-6199     ISO Abbreviation:  Bioanalysis     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101512484     Medline TA:  Bioanalysis     Country:  England    
Other Details:
Languages:  eng     Pagination:  751-67     Citation Subset:  IM    
Affiliation:
Stable Isotope Unit, James Hutton Institute, Invergowrie, Dundee, DD2 5DA, UK. wolfram.meier-augenstein@hutton.ac.uk.
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