Document Detail

Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU.
MedLine Citation:
PMID:  18219516     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality. AIM: To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants. METHODS: The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life. RESULTS: A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality. CONCLUSIONS: The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
J Janota; J Simak; Z Stranak; T Matthews; T Clarke; D Corcoran
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Publication Detail:
Type:  Journal Article     Date:  2008-01-25
Journal Detail:
Title:  Irish journal of medical science     Volume:  177     ISSN:  1863-4362     ISO Abbreviation:  Ir J Med Sci     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-07-03     Completed Date:  2008-08-28     Revised Date:  2009-05-21    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  11-7     Citation Subset:  IM    
Department of Paediatrics, The Rotunda Hospital, Parnell Square, Dublin 1, Ireland.
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MeSH Terms
Critical Illness
Hospital Mortality
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Intensive Care Units, Neonatal
Multiple Organ Failure / diagnosis*,  mortality
Predictive Value of Tests
Reproducibility of Results
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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