| Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU. | |
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MedLine Citation:
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PMID: 18219516 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality. AIM: To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants. METHODS: The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life. RESULTS: A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality. CONCLUSIONS: The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality. |
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Authors:
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J Janota; J Simak; Z Stranak; T Matthews; T Clarke; D Corcoran |
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Publication Detail:
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Type: Journal Article Date: 2008-01-25 |
Journal Detail:
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Title: Irish journal of medical science Volume: 177 ISSN: 1863-4362 ISO Abbreviation: Ir J Med Sci Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-07-03 Completed Date: 2008-08-28 Revised Date: 2009-05-21 |
Medline Journal Info:
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Nlm Unique ID: 7806864 Medline TA: Ir J Med Sci Country: Ireland |
Other Details:
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Languages: eng Pagination: 11-7 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, The Rotunda Hospital, Parnell Square, Dublin 1, Ireland. janjanota@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Critical Illness Female Hospital Mortality Humans Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Intensive Care Units, Neonatal Male Multiple Organ Failure / diagnosis*, mortality Predictive Value of Tests Prognosis Reproducibility of Results Severity of Illness Index |
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