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Critical review or scientific opinion paper: Arsenosugars-a class of benign arsenic species or justification for developing partly speciated arsenic fractionation in foodstuffs?
MedLine Citation:
PMID:  20972554     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In this opinion paper the toxicokinetic behaviour of arsenosugars is reviewed and compared with that of inorganic arsenic and arsenobetaine. It is concluded that the arsenosugars are similar to inorganic arsenic in terms of metabolite formation and tissue accumulation. As a pragmatic means of generating uniform data sets which adequately represent the toxicity of arsenic in food we recommend reporting partly speciated arsenic concentrations in food commodities in three fractions: i) toxic inorganic arsenic as arsenate (after oxidation); ii) arsenobetaine as established non-toxic arsenic; and iii) potentially toxic arsenic, which includes arsenosugars and other organoarsenicals.
Authors:
Jörg Feldmann; Eva M Krupp
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Publication Detail:
Type:  Journal Article     Date:  2010-10-23
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  399     ISSN:  1618-2650     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1735-41     Citation Subset:  IM    
Affiliation:
TESLA Trace Element Speciation Laboratory, University of Aberdeen, Aberdeen, AB24 3UE, Scotland, UK, j.feldmann@abdn.ac.uk.
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