| Critical limb ischemia: endovascular strategies for limb salvage. | |
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MedLine Citation:
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PMID: 21722787 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease, defined as the presence of chronic ischemic rest pain, ulcers, or gangrene attributable to objectively proven arterial occlusive disease. The dominant pathology underlying CLI is atherosclerosis, distributed at multiple levels along the length of the lower extremity and with a propensity for involvement of the tibial vessels in the leg and the small vessels of the foot. To achieve limb salvage in patients with CLI, revascularization of the affected limb is generally required. In contemporary practice, endovascular techniques are rapidly replacing surgical bypass as the first option for revascularization for CLI based on high technical success rates and low rates of procedure-related morbidity and mortality. This review will describe the clinical strategy of the authors who have adopted an endovascular-first approach to revascularization in treating patients with CLI and summarize the clinical outcomes of endovascular therapy in this population. |
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Authors:
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Philip B Dattilo; Ivan P Casserly |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Progress in cardiovascular diseases Volume: 54 ISSN: 1873-1740 ISO Abbreviation: Prog Cardiovasc Dis Publication Date: 2011 Jul-Aug |
Date Detail:
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Created Date: 2011-07-04 Completed Date: 2011-09-06 Revised Date: 2013-05-02 |
Medline Journal Info:
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Nlm Unique ID: 0376442 Medline TA: Prog Cardiovasc Dis Country: United States |
Other Details:
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Languages: eng Pagination: 47-60 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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University of Colorado, Aurora, CO 80045, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Amputation Endovascular Procedures* / adverse effects Female Humans Ischemia / diagnosis, therapy* Limb Salvage* Lower Extremity / blood supply* Male Middle Aged Severity of Illness Index Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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