Document Detail

Critical limb ischaemia: a case against Consensus II.
MedLine Citation:
PMID:  8708426     Owner:  NLM     Status:  MEDLINE    
Critical limb ischaemia (CLI) is a serious clinical condition that often immediately precedes limb loss. The Consensus Documents of 1989 and 1991 attempted to define CLI and give direction to its investigation and management. Whilst the need for such a consensus was clear and should be supported we believe the definition of CLI as documented in the Consensus Documents I and II recommendation number I is wrong. We present evidence from 140 patients with severe limb ischaemia taken from the PARTNER Group studies to support our request for an amendment to the ankle pressure recommendation from < or = 50 mmHg to >50 mmHg and big toe pressure from < or = 30 mmHg to >30 mmHg for the purpose of conducting clinical trials and to include Doppler index and tcPO2 as additional parameters. We also believe that the current document may be actually excluding the only group of patients likely to benefit from drug treatment or other interventions and that the above amendment should be prioritized.
J J Belch; C Diehm; M Söhngen; W Söhngen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  14     ISSN:  0392-9590     ISO Abbreviation:  Int Angiol     Publication Date:  1995 Dec 
Date Detail:
Created Date:  1996-09-12     Completed Date:  1996-09-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  353-6     Citation Subset:  IM    
Department of Medicine, Ninewells Hospital and Medical-School, University of Dundee, Scotland.
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MeSH Terms
Blood Pressure
Cardiovascular Agents / therapeutic use
Combined Modality Therapy
Consensus Development Conferences as Topic
Epoprostenol / analogs & derivatives,  therapeutic use
Follow-Up Studies
Ischemia* / mortality,  physiopathology,  therapy
Leg / blood supply*,  physiopathology,  surgery
Peripheral Vascular Diseases* / mortality,  physiopathology,  therapy
Prostaglandins, Synthetic / therapeutic use
Retrospective Studies
Survival Rate
Treatment Outcome
Vascular Surgical Procedures
Reg. No./Substance:
0/Cardiovascular Agents; 0/Prostaglandins, Synthetic; 35121-78-9/Epoprostenol; 87440-45-7/taprostene

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