| Critical evaluation of the efficacy and tolerability of azilsartan. | |
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MedLine Citation:
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PMID: 22661897 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Appropriate control of blood pressure (BP) in hypertensive patients still represents the major therapeutic goal in the treatment of hypertension. Despite the growing attention and wide range of antihypertensive agents available in the clinical scenario, the target of BP below the advised thresholds of 140/90 mmHg is, unfortunately, often unreached. For this reason, the search for new antihypertensive agents is still ongoing. Azilsartan medoxomil, a new angiotensin receptor blocker that has been recently introduced in the clinical arena, represents the eighth angiotensin receptor blocker currently available for BP control. The aim of this paper is to describe the efficacy and safety profile of this new compound, reviewing available data obtained from both pre-clinical and clinical studies. |
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Authors:
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Alberto R De Caterina; Andrew R Harper; Florim Cuculi |
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Publication Detail:
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Type: Journal Article; Review Date: 2012-05-14 |
Journal Detail:
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Title: Vascular health and risk management Volume: 8 ISSN: 1178-2048 ISO Abbreviation: Vasc Health Risk Manag Publication Date: 2012 |
Date Detail:
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Created Date: 2012-06-04 Completed Date: 2012-09-04 Revised Date: 2013-02-22 |
Medline Journal Info:
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Nlm Unique ID: 101273479 Medline TA: Vasc Health Risk Manag Country: New Zealand |
Other Details:
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Languages: eng Pagination: 299-305 Citation Subset: IM |
Affiliation:
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Istituto Scienze della Vita, Scuola Superiore Sant'Anna, Pisa, Italy. adecatro@yahoo.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiotensin II Type 1 Receptor Blockers
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adverse effects,
pharmacokinetics,
therapeutic use* Animals Antihypertensive Agents / adverse effects, pharmacokinetics, therapeutic use* Benzimidazoles / adverse effects, pharmacokinetics, therapeutic use* Blood Pressure / drug effects* Drug Interactions Evidence-Based Medicine Humans Hypertension / drug therapy*, physiopathology Oxadiazoles / adverse effects, pharmacokinetics, therapeutic use* Renin-Angiotensin System / drug effects Risk Assessment Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin II Type 1 Receptor Blockers; 0/Antihypertensive Agents; 0/Benzimidazoles; 0/Oxadiazoles; 0/azilsartan medoxomil; F9NUX55P23/azilsartan |
| Comments/Corrections | |
Erratum In:
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Vasc Health Risk Manag. 2012;8:443-5 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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