Document Detail

Critical evaluation of the different staging systems for hepatocellular carcinoma.
MedLine Citation:
PMID:  15048738     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Diagnostic and therapeutic options for hepatocellular carcinoma (HCC) have improved substantially in recent years. A number of new palliative and potentially curative treatment strategies are now available. However, evaluation of the therapeutic modalities and assessment of the prognosis of HCC remain difficult owing to the lack of consensus on a single staging system and the availability of a number of new staging systems, each claiming to be the most appropriate. METHODS: The most frequently used staging systems for HCC are presented here. Their ability to stratify patients into different treatment groups and to define prognosis are discussed. In addition, the advantages and disadvantages of each system are analysed. RESULTS AND CONCLUSION: None of the currently used staging systems fulfils all the requirements for stratification of patients with HCC into groups of different prognosis and therapeutic recommendations. An international agreement on a single staging system is urgently needed in order to permit comparable randomized clinical trials. Only in this way will the outcome for those with HCC be improved.
S Wildi; B C Pestalozzi; L McCormack; P-A Clavien
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The British journal of surgery     Volume:  91     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-29     Completed Date:  2004-05-10     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  400-8     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2004 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Department of Visceral and Transplantation Surgery, University Hospital of Zurich, 8091 Zurich, Switzerland.
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MeSH Terms
Carcinoma, Hepatocellular / pathology*
Liver Neoplasms / pathology*
Neoplasm Metastasis
Neoplasm Staging / methods*
Comment In:
Br J Surg. 2004 Aug;91(8):1072   [PMID:  15286973 ]

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