| Critical evaluation of the cocaine test in the diagnosis of Horner's syndrome. | |
| | |
MedLine Citation:
|
PMID: 2310339 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We evaluated the effectiveness of the cocaine test for diagnosing Horner's syndrome. The test was administered to 119 patients with a diagnosis of Horner's syndrome and to 50 normal subjects. We compared the cocaine-induced anisocoria in the two groups by measuring photographs of the pupils. We found the cocaine test to be highly effective in separating normal subjects from patients with Horner's syndrome. The chances of having Horner's syndrome increased with the amount of cocaine-induced anisocoria. Through the use of logistic regression analysis, we determined the odds ratio of having Horner's syndrome compared with not having it for each 0.1-mm increment of anisocoria measured after cocaine administration. A postcocaine anisocoria value of 0.8 mm gave a mean odds ratio of approximately 1050:1 that Horner's syndrome was present (lower 95% confidence limit = 37:1). We found that simply measuring the postcocaine anisocoria provided a better prediction of Horner's syndrome than taking the trouble to calculate the net change in anisocoria. Odds ratios should help the clinician decide if the result of a cocaine test is indicative of Horner's syndrome. |
| | |
Authors:
|
R H Kardon; C E Denison; C K Brown; H S Thompson |
Related Documents
:
|
9164889 - The pacemaker syndrome -- a matter of definition. 9184319 - Additional clinical and cytogenetic findings associated with rett syndrome. 7995799 - Fragile x syndrome in a normal iq male with learning and emotional problems. 12102209 - Trigeminal and polyradiculoneuritis in a dog presenting with masticatory muscle atrophy... 17214089 - Skull base osteomyelitis presenting as villaret's syndrome. 15093849 - A child with isolated horner's syndrome after blunt neck trauma. 19294559 - Distinct neutrophil subpopulations phenotype by flow cytometry in myelodysplastic syndr... 1554559 - Wolff-parkinson-white syndrome. 3568439 - Ichthyosis-cheek-eyebrow (ice) syndrome: a new autosomal dominant disorder. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of ophthalmology Volume: 108 ISSN: 0003-9950 ISO Abbreviation: Arch. Ophthalmol. Publication Date: 1990 Mar |
Date Detail:
|
Created Date: 1990-04-12 Completed Date: 1990-04-12 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7706534 Medline TA: Arch Ophthalmol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 384-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Ophthalmology, University of Iowa Hospital, Iowa City 52242. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Analysis of Variance Anisocoria / chemically induced Case-Control Studies Cocaine / diagnostic use* Evaluation Studies as Topic Female Horner Syndrome / diagnosis* Humans Male Middle Aged Odds Ratio Photography Predictive Value of Tests Pupil / drug effects Regression Analysis |
| Chemical | |
Reg. No./Substance:
|
50-36-2/Cocaine |
| Comments/Corrections | |
Comment In:
|
Arch Ophthalmol. 1990 Dec;108(12):1667-8
[PMID:
2256827
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Eye injuries in children in Israel. A nationwide collaborative study.
Next Document: Management of congenital lacrimal sac fistula.