Document Detail

Critical aortic stenosis. Survival and management.
MedLine Citation:
PMID:  3657253     Owner:  NLM     Status:  MEDLINE    
The factors associated with survival in 40 neonates (age less than 28 days) with critical aortic stenosis undergoing either open (22 patients) or closed (18 patients) transventricular aortic valvotomy were reviewed. Significant adverse correlates with survival included evidence of poor perfusion preoperatively (low pH, greater than Grade 2/6 soft ejection systolic murmur) and marked congestive heart failure (hepatomegaly, cardiomegaly, elevated left atrial pressure). Congenital mitral stenosis (anulus less than 11 mm), a small aortic anulus (less than 6.5 mm), and failure to achieve an adequate aortic orifice (greater than 6 mm), at operation were identified as factors associated with increased mortality. Initial perioperative survival was better with closed aortic valvotomy. However, there was no significant difference in overall operative survival between closed (9/18, 50%) and open (8/22, 36%) aortic valvotomy (p = 0.26). The incidence of early reoperation (less than 1 year of age) was greater in perioperative survivors undergoing closed valvotomy (7/13, 54%) rather than open valvotomy (1/10, 10%) (p less than 0.05). In conclusion, long-term survival among patients with critical neonatal aortic valve stenosis remains disturbingly low (13/40, 32%) and has not significantly improved over the past 20 years.
A N Pelech; J D Dyck; G A Trusler; W G Williams; P M Olley; R D Rowe; R M Freedom
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  94     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-10     Completed Date:  1987-11-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  510-7     Citation Subset:  AIM; IM    
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Aortic Valve / surgery
Aortic Valve Stenosis / mortality,  physiopathology,  surgery*
Follow-Up Studies
Heart Catheterization
Infant, Newborn
Mitral Valve Insufficiency / complications
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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