| Critical analysis of the performance of double-contrast barium enema for detecting colorectal polyps > or = 6 mm in the era of CT colonography. | |
| | |
MedLine Citation:
|
PMID: 18212223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of our study was to perform a meta-analysis comparing the performance of double-contrast barium enema (DCBE) with CT colonography (CTC) for the detection of colorectal polyps > or = 6 mm using endoscopy as the gold standard. MATERIALS AND METHODS: Prospective DCBE and CTC studies were identified. Percentages of polyps and of patients with polyps > or = 10 mm and 6-9 mm were abstracted. The performance of DCBE versus CTC was determined by separately evaluating each technique's performance versus that of endoscopy, and contrasting the techniques. The I-squared statistic and Fisher's exact test were used for heterogeneity, the Cochran-Mantel-Haenszel and the Kruskal-Wallis tests for correlation, and the A(z) test for comparing pooled weighted estimates of performance. RESULTS: Eleven studies of DCBE (5,995 patients, 1,548 polyps) and 30 studies of CTC (6,573 patients, 2,348 polyps) fulfilled inclusion criteria. For polyps > or = 10 mm, a 0.121-per-patient sensitivity difference favored CTC (p < 0.0001; DCBE, 0.702 [95% CI, 0.687-0.715]; CTC, 0.823 [0.809-0.836]). For polyps > or = 10 mm, a 0.031-per-polyp sensitivity difference favored CTC (p < 0.0001; DCBE, 0.715 [0.703-0.726]; CTC, 0.746 [0.735-0.757]). For polyps > or = 10 mm, a specificity difference of 0.104 favored CTC (p = 0.001; DCBE, 0.850 [0.847-0.855]; CTC, 0.954 [0.952-0.955]). DCBE was also significantly less sensitive for 6- to 9-mm polyps (p < 0.001). CONCLUSION: DCBE has statistically lower sensitivity and specificity than CTC for detecting colorectal polyps > or = 6 mm. |
| | |
Authors:
|
Jacob Sosna; Tamar Sella; Oumar Sy; Philip T Lavin; Ruth Eliahou; Shifra Fraifeld; Eugene Libson |
Related Documents
:
|
22340943 - Prenatally diagnosed fetal conditions in the age of fetal care: does who counsels matter? 12437853 - Helmet design to facilitate thermoneutrality during forest harvesting. 21295843 - Effects of timing of induced luteolysis in embryo donor mares on reproductive performan... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Meta-Analysis; Review |
Journal Detail:
|
Title: AJR. American journal of roentgenology Volume: 190 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2008 Feb |
Date Detail:
|
Created Date: 2008-01-23 Completed Date: 2008-02-11 Revised Date: 2008-02-15 |
Medline Journal Info:
|
Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
|
Languages: eng Pagination: 374-85 Citation Subset: AIM; IM |
Affiliation:
|
Department of Radiology, Hadassah Hebrew University Medical Center, POB 12000, Jerusalem, Israel. jacobs@hadassah.org.il |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Barium Sulfate
/
administration & dosage*,
diagnostic use* Colonic Polyps / epidemiology*, radiography* Colonography, Computed Tomographic / statistics & numerical data* Enema Female Humans Intestinal Polyps / epidemiology, radiography Male Prevalence Reproducibility of Results Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
|
7727-43-7/Barium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Imaging findings in Roux-en-O and other misconstructions: rare but serious complications of Roux-en-...
Next Document: 3-T contrast-enhanced MR angiography in evaluation of suspected intracranial aneurysm: comparison wi...