Document Detail


Crimean-Congo haemorrhagic fever cases in Turkey.
MedLine Citation:
PMID:  17454897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Crimean-Congo haemorrhagic fever (CCHF) is an arbovirus infection, which is transmitted through ticks or via blood and secretions. Until recently, human cases of CCHF were unknown in Turkey; however, several acute disease cases were reported in 2002. We report on the investigation of a cluster of suspected CCHF cases in the middle part of the Black Sea from May 2002 to October 2003. The medical charts that we reviewed were obtained from all local physicians and our field investigations. 'Suspected case' was defined with regard to time, place, and both clinical and laboratory characteristics. A total of 108 patients were defined as suspected case. Among them 36 patients were reached and blood samples taken for examination for CCHF by using ELISA and RT-PCR. According to the laboratory analysis, 80.6% (29/36) were acute cases and 8.3% (3/36) were past CCHF infections. The overall mortality rate was 5.6%. There was no nosocomial infection; however, there were 2 family clusters. Tick exposure was the most prevalent risk factor (74.2%). A multidisciplinary collaboration should be developed in order to understand the magnitude of the disease and also to keep it under control.
Authors:
Aysegul Gozalan; Berrin Esen; Julia Fitzner; Fatih Sua Tapar; Ayse Peker Ozkan; Marie-Claude Georges-Courbot; Ramazan Uzun; Feyzullah Gumuslu; Levent Akin; Hervé Zeller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  39     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  2007  
Date Detail:
Created Date:  2007-04-24     Completed Date:  2007-05-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  332-6     Citation Subset:  IM    
Affiliation:
Department of Communicable Diseases Research, Refik Saydam National Hygiene Centre, Ankara, Sihhiye, Turkey. agozalan@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Viral / blood*
Disease Outbreaks*
Female
Hemorrhagic Fever Virus, Crimean-Congo / immunology*,  pathogenicity
Hemorrhagic Fever, Crimean / diagnosis,  epidemiology,  immunology*
Humans
Male
Tick-Borne Diseases / epidemiology
Turkey / epidemiology
Chemical
Reg. No./Substance:
0/Antibodies, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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