| Crib death: further support for the concept of fatal cardiac electrical instability as the final common pathway. | |
| | |
MedLine Citation:
|
PMID: 14602212 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This work intends to be a review of the current status of knowledge on the cardiac conduction system in the crib death as well as remaining challenges, including reflections upon authors' personal works as well as many studies by others. The cardiac conduction system findings of resorptive degeneration, His bundle dispersion, Mahaim fibers, cartilaginous meta-hyperplasia, persistent fetal dispersion, left sided His bundle, hemorrhage of the atrio-ventricular junction, septation of the bifurcation, atrio-ventricular node dispersion, sinus node hypoplasia, Zahn node, His bundle hypoplasia, atrio-ventricular node and His bundle dualism are hereby discussed by the authors. The cardiac hypotheses postulating that crib death could be due to lethal cardiac arrhythmias or heart block were considered of great interest in the 1970s. After a general abandon of the conduction studies in crib death, the cardiac concept of crib death is gathering a renewed interest, as well as the occurrence of infantile junctional tachycardia. Both the morphological and functional derangement underlying crib death remain poorly understood, assuring that it remains to be a major medical and social problem. Despite the non-specificity of most of the cardiac conduction findings in crib death, we believe that they, in association with altered neurovegetative stimuli, could underlie potentially malignant arrhythmias, providing a morphologic support for the cardiac concept of crib death. |
| | |
Authors:
|
Giulia Ottaviani; Luigi Matturri; Lino Rossi; Thomas N James |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: International journal of cardiology Volume: 92 ISSN: 0167-5273 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2003 Nov |
Date Detail:
|
Created Date: 2003-11-06 Completed Date: 2004-03-18 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Ireland |
Other Details:
|
Languages: eng Pagination: 17-26 Citation Subset: IM |
Affiliation:
|
Institute of Pathology, University of Milan, Via della Commenda 19, 20122 Milan, Italy. giulia.ottaviani@unimi.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Apoptosis Heart Conduction System / pathology, physiopathology* Humans Infant Long QT Syndrome / physiopathology* Myocardium / pathology Sudden Infant Death* / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Natriuretic peptide measurement as a screening test for overt and subclinical heart failure.
Next Document: C-reactive protein on admission and the success of thrombolytic therapy with streptokinase: is there...