Document Detail


Crevicular fluid myeloperoxidase at healthy, gingivitis and periodontitis sites.
MedLine Citation:
PMID:  2536761     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The volume and myeloperoxidase (MPO) activity of gingival crevicular fluid (GCF) collected with filter paper strips for 30 s from the sulcus of healthy, gingivitis and periodontitis sites of Chinese subjects were measured. MPO/site and MPO/microliter GCF were both greater at gingivitis and periodontitis sites than at healthy sites. Enzyme activity was similar at the 2 categories of diseased sites. Mean GCF volume and MPO activity were calculated for all samples from healthy, gingivitis and periodontitis sites with GI 0, 1, 2 and 0 + 1. GCF volume, MPO/site and MPO/microliter GCF all were greater at GI 2 than GI 0 or 0 + 1. These data indicate that increased GCF MPO previously observed at periodontitis sites is not specific to such sites. Rather increased GCF MPO likely occurs when additional polymorphonuclear leukocytes enter the sulcus as a result of gingival inflammation. A second sample was obtained from 22 sites 4 weeks after the initial collection. These samples were collected for 5 s rather than 30 s. The GCF volume, MPO/site and MPO/microliters GCF were each greater in samples collected for 30 s rather than 5 s. Correlation coefficients showed that the amount of GCF and MPO activity of the fluid collected for 5 s and 30 s was dependent upon the site even though the 5-s and 30-s samples were collected 4 weeks apart.
Authors:
C F Cao; Q T Smith
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical periodontology     Volume:  16     ISSN:  0303-6979     ISO Abbreviation:  J. Clin. Periodontol.     Publication Date:  1989 Jan 
Date Detail:
Created Date:  1989-03-14     Completed Date:  1989-03-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0425123     Medline TA:  J Clin Periodontol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  17-20     Citation Subset:  D; IM    
Affiliation:
Department of Periodontology, University of Minnesota School of Dentistry.
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MeSH Terms
Descriptor/Qualifier:
Adult
China
Gingiva / enzymology
Gingival Crevicular Fluid / enzymology*
Gingivitis / enzymology*
Humans
Male
Periodontal Index
Periodontitis / enzymology*
Peroxidase / metabolism*
Chemical
Reg. No./Substance:
EC 1.11.1.7/Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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