| Creation of a Lipase Highly Selective for trans Fatty Acids by Protein Engineering. | |
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MedLine Citation:
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PMID: 22113941 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Sorting out: Protein engineering of lipase CAL-A led to the discovery of mutants with excellent chemoselectivity for the removal of trans and saturated fatty acids from partially hydrogenated vegetable oil. These fatty acids, identified as a major risk factor for human health, can now be removed by enzyme catalysis. |
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Authors:
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Henrike B Brundiek; Andrew S Evitt; Robert Kourist; Uwe T Bornscheuer |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-23 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Institut für Biochemie, Abt. Biotechnologie & Enzymkatalyse, Universität Greifswald, Felix-Hausdorff-Strasse 4, 17487 Greifswald (Germany). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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