Document Detail

Creatine supplementation does not enhance submaximal aerobic training adaptations in healthy young men and women.
MedLine Citation:
PMID:  16896727     Owner:  NLM     Status:  MEDLINE    
The benefits of dietary creatine supplementation on muscle performance are generally related to an increase in muscle phosphocreatine content. However, creatine supplementation may benefit endurance sports through increased glycogen re-synthesis following exercise. This study investigated the effect of creatine supplementation on muscle glycogen content, submaximal exercise fuel utilisation and endurance performance following 4 weeks of endurance training. Thirteen healthy, physically active, non-vegetarian subjects volunteered to take part and completed the study. Subjects were supplemented with either creatine monohydrate (CREAT, n = 7) or placebo-maltodextrin (CON, n = 6). Submaximal fuel utilisation and endurance performance were assessed before and after a 4 week endurance training program. Muscle biopsies were also collected before and following training for assessment of muscle creatine and glycogen content. Training increased quadriceps glycogen content to the same degree (approximately 20%) in both groups (P = 0.04). There was a significant training effect on submaximal fuel utilisation and improved endurance performance. However, there was no significant treatment effect of creatine supplementation. Creatine supplementation does not effect metabolic adaptations to endurance training.
T F Reardon; P A Ruell; M A Fiatarone Singh; C H Thompson; K B Rooney
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Publication Detail:
Type:  Journal Article     Date:  2006-08-09
Journal Detail:
Title:  European journal of applied physiology     Volume:  98     ISSN:  1439-6319     ISO Abbreviation:  Eur. J. Appl. Physiol.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-21     Completed Date:  2007-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954790     Medline TA:  Eur J Appl Physiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  234-41     Citation Subset:  IM    
School of Exercise and Sport Science, Faculty of Health Sciences, University of Sydney, C42-Cumberland Campus, Lidcombe, NSW, Australia.
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MeSH Terms
Adaptation, Physiological*
Carbohydrates / chemistry
Creatine / pharmacology*
Dietary Supplements*
Exercise / physiology*
Fats / metabolism
Glycogen / analysis
Muscle, Skeletal / drug effects,  metabolism
Physical Endurance / drug effects*,  physiology
Reg. No./Substance:
0/Carbohydrates; 0/Fats; 57-00-1/Creatine; 9005-79-2/Glycogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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