| Craniovertebral junction tuberculosis: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 20232104 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Craniovertebral junction tuberculosis (CVJ TB) is a rare disease, potentially causing significant neurological deficits and even death. We report on a 80-year-old woman presenting with CVJ TB without pulmonary involvement. The diagnosis was made by biopsy of the cervical lymph node showing granulomatous caseation necrosis. Despite extensive erosion of the clivus, C1, and C2, and spinal cord compression, the patient was effectively managed with antituberculous drug therapy and conservative neck stabilization. Neck pain resulting from cervical spondylosis is common in elderly people. However, even if there is no obvious pulmonary involvement, CVJ TB should be considered in the differential diagnosis, especially in patients with painful neck stiffness. The most useful method available for evaluating this region is a combination of CT scan and MRI study. CVJ TB can be managed conservatively, except for a selected few cases, regardless of the extent of bony destruction. |
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Authors:
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Chisho Hoshino; Masashi Narita |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-03-16 |
Journal Detail:
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Title: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Volume: 16 ISSN: 1437-7780 ISO Abbreviation: J. Infect. Chemother. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-05 Completed Date: 2010-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9608375 Medline TA: J Infect Chemother Country: Japan |
Other Details:
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Languages: eng Pagination: 288-91 Citation Subset: IM |
Affiliation:
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General Internal Medicine, Ohta-Nishinouchi Hospital, Koriyama, Fukushima 963-8558, Japan. gim-hoshino@ohta-hp.or.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Antitubercular Agents / therapeutic use Cranial Fossa, Posterior / microbiology, pathology Female Humans Lymphatic Diseases / microbiology Magnetic Resonance Imaging Mycobacterium tuberculosis / genetics, isolation & purification* Neck Pain / microbiology Spinal Cord Compression / microbiology, pathology Tomography, X-Ray Computed Tuberculosis, Spinal / diagnosis*, drug therapy, pathology |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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