Document Detail


Craniospinal irradiation using a forward planned segmented field technique.
MedLine Citation:
PMID:  17121758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Craniospinal irradiation is technically demanding due to the complex shape of the planning target volume (PTV). Radiotherapy treatment techniques have evolved over time as imaging and radiotherapy treatment technology have improved. However, most are variations on a class solution utilizing a prone patient position with two shaped lateral cranial portals and a matched posterior spinal portal with moving junctions. Major areas of difficulty remain with the accurate definition of the PTV and achieving a homogeneous dose within it, especially at the junctions. We describe a three-dimensionally (3D) planned craniospinal radiation technique that permits rapid image acquisition with reduced localization time, simplified spinal PTV definition and standardized cranial PTV definition. Improved dose homogeneity within the PTV is achieved by use of a segmented "field-in-field" technique (forward planned intensity-modulated radiotherapy (IMRT)) in place of customized compensators. This has negated the requirement for constructing physical compensators. Autosequencing for field delivery enables the junction to be "moved" during a single fraction and reduces the overall treatment time, an important consideration when treating very young patients.
Authors:
J M Wilkinson; J Lewis; G P Lawrence; H H Lucraft; E Murphy
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2006-11-22
Journal Detail:
Title:  The British journal of radiology     Volume:  80     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-06-05     Completed Date:  2007-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-15     Citation Subset:  AIM; IM    
Affiliation:
Regional Medical Physics Department, Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK.
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MeSH Terms
Descriptor/Qualifier:
Brain Neoplasms / radiography,  radiotherapy
Central Nervous System Neoplasms / radiography,  radiotherapy*
Cerebellar Neoplasms / radiography,  radiotherapy
Humans
Medulloblastoma / radiography,  radiotherapy
Particle Accelerators
Prone Position
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods*
Spinal Neoplasms / radiography,  radiotherapy
Tomography, X-Ray Computed / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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