Document Detail

Craniospinal dissemination of central neurocytoma. Report of two cases.
MedLine Citation:
PMID:  9046315     Owner:  NLM     Status:  MEDLINE    
Central neurocytoma was first described in the literature in 1982 and has been noted to be a benign neuronal tumor usually located in the ventricular system. Of the more than 100 reported cases, only seven recurrences have been reported, all of which have been local. The authors report two cases of recurrent central neurocytoma that disseminated through the ventricular system with seeding to the spine, as evidenced by magnetic resonance images and positive cerebrospinal fluid cytology. The histological appearance of these two tumors was typical for the lesion and lacked evidence of malignant change. Central neurocytoma may not be as benign as previously thought, and the recognition of this more malignant behavior has implications for patient follow up and therapy.
D Y Eng; F DeMonte; L Ginsberg; G N Fuller; K Jaeckle
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  86     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-03-24     Completed Date:  1997-03-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  547-52     Citation Subset:  AIM; IM    
Department of Neurosurgery, University of Texas, M. D. Anderson Cancer Center, Houston, USA.
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MeSH Terms
Antineoplastic Agents / administration & dosage
Antineoplastic Agents, Alkylating / administration & dosage
Antineoplastic Agents, Phytogenic / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cerebral Ventricle Neoplasms / cerebrospinal fluid,  drug therapy,  pathology*,  surgery
Cisplatin / administration & dosage
Cyclophosphamide / administration & dosage
Dura Mater / pathology
Etoposide / administration & dosage
Follow-Up Studies
Magnetic Resonance Imaging
Neoplasm Recurrence, Local / pathology
Neoplasm Seeding
Neoplastic Cells, Circulating / pathology
Neurocytoma / cerebrospinal fluid,  drug therapy,  pathology*,  surgery
Septum Pellucidum / pathology
Spinal Cord Neoplasms / cerebrospinal fluid,  drug therapy,  pathology*
Reg. No./Substance:
0/Antineoplastic Agents; 0/Antineoplastic Agents, Alkylating; 0/Antineoplastic Agents, Phytogenic; 15663-27-1/Cisplatin; 33419-42-0/Etoposide; 50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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