Document Detail


Cranial magnetic resonance imaging in chronic demyelinating polyneuropathy.
MedLine Citation:
PMID:  2123236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty one patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and five patients with chronic demyelinating polyneuropathy associated with benign monoclonal paraproteinaemia none of whom had signs or symptoms of central nervous system disease, had cranial magnetic resonance imaging (MRI) on a 1.5 Tesla unit. Areas of increased white matter signal intensity were seen in one of 10 patients aged less than 50 years and in five of 16 patients aged more than 50 years. In only two of the patients (8%), neither of whom had paraproteinaemia, did the appearance strongly suggest demyelination. The only clinical variable that predicted MRI changes was age (p less than 0.01).
Authors:
S H Hawke; J M Hallinan; J G McLeod
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  53     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1991-01-10     Completed Date:  1991-01-10     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  794-6     Citation Subset:  IM    
Affiliation:
Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Brain / pathology
Brain Diseases / diagnosis*
Demyelinating Diseases / diagnosis*
Female
Follow-Up Studies
Humans
Immunoglobulin kappa-Chains / analysis
Immunoglobulin lambda-Chains / analysis
Magnetic Resonance Imaging*
Male
Middle Aged
Monoclonal Gammopathy of Undetermined Significance / complications
Polyradiculoneuropathy / diagnosis*
Chemical
Reg. No./Substance:
0/Immunoglobulin kappa-Chains; 0/Immunoglobulin lambda-Chains
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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