Document Detail


Cranial edema associated with a protein-losing nephropathy in a golden-mantled flying fox (Pteropus pumilus).
MedLine Citation:
PMID:  10367654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An adult golden-mantled flying fox (Pteropus pumilus) was diagnosed with nephrotic syndrome on the basis of the findings of proteinuria, hypoalbuminemia, hypercholesterolemia, and cranial edema. Membranoproliferative glomerulitis and interstitial nephritis were confirmed antemortem by renal biopsy. The bat had received seven injections of oxytocin in the period immediately prior to presentation. The possible role of oxytocin in the development of the nephropathy is discussed. Supportive care and treatment with a single plasma transfusion, furosemide, and prednisone led to a gradual but complete resolution of the nephrotic syndrome in this animal.
Authors:
S L Deem; D J Heard; T L Clippinger; C D Buergelt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  30     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-11-22     Completed Date:  1999-11-22     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  126-31     Citation Subset:  IM    
Affiliation:
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0126, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Chemical Analysis / veterinary
Blood Transfusion / veterinary
Chiroptera*
Diagnosis, Differential
Diuretics / therapeutic use
Edema / blood,  etiology,  veterinary*
Female
Furosemide / therapeutic use
Glucocorticoids / therapeutic use
Hematologic Tests / veterinary
Kidney / pathology
Liver / pathology
Nephrotic Syndrome / complications,  therapy,  veterinary*
Oxytocin / adverse effects
Prednisone / therapeutic use
Skull*
Chemical
Reg. No./Substance:
0/Diuretics; 0/Glucocorticoids; 50-56-6/Oxytocin; 53-03-2/Prednisone; 54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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