| Coxiella burnetii causing haemophagocytic syndrome: a rare complication of an unusual pathogen. | |
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MedLine Citation:
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PMID: 21713429 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We describe an unusual presentation of Q fever with associated haemophagocytic syndrome, confirmed by bone marrow aspirate, Q fever polymerase chain reaction (PCR) and serological testing. Clinical recovery was observed after the commencement of doxycycline with normalisation of the patient's full blood count and serum biochemistry. Serial monitoring of the Q fever serology revealed the subsequent development of sustained high phase 1 IgG antibodies, suggestive of chronic Q fever. Although many infectious aetiologies have been associated with haemophagocytosis, Q fever has only rarely been described in this context. The diagnosis of Q fever is often overlooked, especially when the presentation is atypical. We describe how the use of PCR testing significantly shortened the interval to definitive diagnosis and helped elucidate the underlying cause of the patient's haematological disorder. |
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Authors:
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P Harris; R Dixit; R Norton |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-29 |
Journal Detail:
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Title: Infection Volume: - ISSN: 1439-0973 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0365307 Medline TA: Infection Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Pathology Queensland, Townsville Hospital, Douglas, QLD, 4811, Australia, patrick.harris@hnehealth.nsw.gov.au. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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