Document Detail


Cow's milk intolerance presenting as necrotizing enterocolitis.
MedLine Citation:
PMID:  564896     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Case history is reported of an infant who was changed from breast to bottle feeding at fourth day of life, who on ninth day developed bilious vomiting and bloody diarrhoea. Later gas was found in colonic wall on X-ray. Necrotizing enterocolitis was diagnosed and infant managed with total intravenous alimentation. On recovery although she tolerated breast milk, return to cow's milk formula lead to return of bloody diarrhoea. Subsequently she thrived on a cow's milk-free diet based on chicken meat formula. At four months after total of 15 ml cow's milk she had an acute anaphylactic reaction. She recovered and is well on milk-free diet. Thus, this infant has recovered from necrotizing enterocolitis but has evidence of persistent cow's milk protein intolerance. The hypothesis is put forward that in this child cow's milk protein played a major role in the pathogenesis of necrotizing enterocolitis.
Authors:
E de Peyer; J Walker-Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Helvetica paediatrica acta     Volume:  32     ISSN:  0018-022X     ISO Abbreviation:  Helv Paediatr Acta     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0373005     Medline TA:  Helv Paediatr Acta     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  509-15     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Weight
Cattle
Enterocolitis, Pseudomembranous / chemically induced*,  diet therapy
Female
Humans
Infant Nutritional Physiological Phenomena
Infant, Newborn
Infant, Newborn, Diseases / chemically induced*
Milk / adverse effects*
Milk Proteins / adverse effects
Milk, Human
Necrosis
Chemical
Reg. No./Substance:
0/Milk Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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