Document Detail

Cow's milk allergy: therapeutic options and immunological aspects.
MedLine Citation:
PMID:  8647060     Owner:  NLM     Status:  MEDLINE    
Adverse reaction to cow's milk and infant formulas are common during infancy. Cow's milk has more than 20 constituents proteins and in principle many are capable of giving rise to an IgE mediated response. The prevalence of cow's milk allergy is between 0.5-10% of the paediatric population (Frier & Kletter, 1970, Gerrard et al., 1973 Foucard, 1985). The clinical diagnosis of cow's milk allergy is difficult because of the great diversity and varying severity of symptoms and is often based on criteria which is then confirmed by challenge with cow's milk (Bock et al., 1988, Wershil & Walker, 1988). There is no doubt that various immunological mechanisms are involved in cow's milk allergy and in recent years a number of researchers have investigated the role of humoral and cell-mediated immunity in the pathogenesis of cow's milk allergy.
T Dean
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  49 Suppl 1     ISSN:  0954-3007     ISO Abbreviation:  Eur J Clin Nutr     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1996-07-25     Completed Date:  1996-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S19-25     Citation Subset:  IM    
University Child Health, Southampton General Hospital.
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MeSH Terms
Bottle Feeding* / adverse effects
Breast Feeding*
Double-Blind Method
Hypersensitivity, Delayed / immunology
Immunoglobulin E / blood
Infant Food* / adverse effects
Milk Hypersensitivity / diagnosis,  diet therapy*,  immunology*
Prospective Studies
Skin Tests
T-Lymphocytes / immunology
Reg. No./Substance:
37341-29-0/Immunoglobulin E

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