Document Detail


Cow's milk allergy, incidence and pathogenetic role of early exposure to cow's milk formula.
MedLine Citation:
PMID:  571665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A study was performed in infants under the age of 12 months born during 1974 and admitted to St. Göran's Children's Hospital with symptoms suggestive of cow's milk allergy (CMA). The aims of the study were to determine the role of early exposure to cow's milk formulas as a predisposing factor to CMA and to estimate the incidence of CMA in infancy. Twenty-five infants fulfilled the criteria for CMA. Available records were reviewed and a careful history was obtained from the mothers on two occasions. The patient group was compared with a control group. Sixteen of the 25 infants were exposed to cow's milk protein during their first week in the nursery for newborns, 6 were exposed before the end of the fourth week of life, and 3 infants were apparently not exposed. All infants were breast fed 3 to 26 weeks before re-exposure and occurrence of symptoms. Infants with CMA were given cow's milk formulas during their first 4 weeks of life significantly more often than infants in the control group (p less than 0.01). The incidence of CMA was approximately 1 : 200. The first 4 weeks after birth seem to be a particularly vulnerable period. Hence, in order to prevent CMA, infant formula should not be given--even occasionally--during this period.
Authors:
G Stintzing; R Zetterström
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica Scandinavica     Volume:  68     ISSN:  0001-656X     ISO Abbreviation:  Acta Paediatr Scand     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-07-28     Completed Date:  1979-07-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0000211     Medline TA:  Acta Paediatr Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  383-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Animals
Asthma / etiology
Breast Feeding
Cattle
Diarrhea, Infantile / etiology
Eczema / etiology
Female
Food Hypersensitivity / epidemiology*,  etiology
Humans
Infant
Infant Food / adverse effects*
Infant Nutrition Disorders / epidemiology*,  etiology
Infant, Newborn
Male
Milk / adverse effects*
Rhinitis / etiology
Sweden
Urticaria / etiology
Vomiting / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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