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Cow's Milk and Linear Growth in Industrialized and Developing Countries.
MedLine Citation:
PMID:  16704349     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The strongest evidence that cow's milk stimulates linear growth comes from observational and intervention studies in developing countries that show considerable effects. Additionally, many observational studies from well-nourished populations also show an association between milk intake and growth. These results suggest that milk has a growth-stimulating effect even in situations where the nutrient intake is adequate. This effect is supported by studies that show milk intake stimulates circulating insulin-like growth factor (IGF)-I, which suggests that at least part of the growth-stimulating effects of milk occur through the stimulation of IGF. Given that the biological purpose of milk is to support the newborn during a period of high growth velocity, such an effect seems plausible. Adding cow's milk to the diet of stunted children is likely to improve linear growth and thereby reduce morbidity. In well-nourished children, the long-term consequences of an increased consumption of cow's milk, which may lead to higher levels of IGF-I in circulation or an increase in the velocity of linear growth, are likely to be both positive and negative. Based on emerging data that suggest both growth and diet during early life program the IGF axis, the association between milk intake and later health is likely to be complex. Expected online publication date for the Annual Review of Nutrition Volume 26 is July 17, 2006. Please see http://www.annualreviews.org/catalog/pub_dates.asp for revised estimates.
Authors:
Camilla Hoppe; Christian Mølgaard; Kim F Michaelsen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2006-4-21
Journal Detail:
Title:  Annual review of nutrition     Volume:  -     ISSN:  1545-4312     ISO Abbreviation:  Annu. Rev. Nutr.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-5-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8209988     Medline TA:  Annu Rev Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Human Nutrition and Center for Advanced Food Studies, The Royal Veterinary and Agricultural University, DK-1958 Frederiksberg C, Denmark.
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