| Covered skin transcutaneous bilirubin estimation is comparable with serum bilirubin during and after phototherapy. | |
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MedLine Citation:
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PMID: 21818063 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine whether transcutaneous bilirubin (TcB) from covered skin (TcB-C) during and after discontinuing phototherapy (PHT) is reliable in treating neonatal jaundice. STUDY DESIGN: In this prospective observational study, before starting PHT, part of the forehead was covered. TcB-C and TcB from exposed skin (TcB-E) to PHT were measured before starting PHT, on a 12-hourly basis while receiving PHT and 6 h after stopping PHT. We used ANOVA (analysis of variance) and Bonferroni's t-tests. RESULT: A total of 39 infants were enrolled (mean gestation 39 weeks, 51% males and 80% Hispanic). The mean TSB over all time periods was 10.9±2.4, TcB-C 10.9±2.4 and TcB-E 7.2±3.4. Before PHT, there were no significant differences in bilirubin by all three techniques. TcB-C was not significantly different from TSB at any time point. However, TcB-E was significantly lower during PHT and after stopping PHT. CONCLUSION: TcB-C is a reliable method in the management of neonatal jaundice. |
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Authors:
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R Fonseca; R Kyralessa; M Malloy; J Richardson; S K Jain |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2011-08-04 |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 32 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-31 Completed Date: 2012-06-04 Revised Date: 2012-10-24 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 129-31 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bilirubin
/
analysis*,
blood Biological Markers / analysis Cohort Studies Female Follow-Up Studies Gestational Age Humans Infant, Newborn Infant, Premature Intensive Care Units, Neonatal Jaundice, Neonatal / diagnosis*, therapy* Male Monitoring, Physiologic / methods Phototherapy / methods* Prospective Studies Reproducibility of Results Sensitivity and Specificity Severity of Illness Index Skin / chemistry* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 635-65-4/Bilirubin |
| Comments/Corrections | |
Comment In:
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J Perinatol. 2012 Sep;32(9):734-5; author reply 735
[PMID:
22931963
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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